Here are the biggest winners among the individual stocks in the S&P over that time frame:
- Netflix, up 6,998.5 percent
- Amazon.com, up 2,321.4 percent
- Align Technology, up 2,316 percent
- Regneron Pharmaceuticals, up 1,869.6 percent
- Booking Holdings, up 1,738.9 percent
Netflix and Amazon are familiar names. Align technology makes the Invisalign dental device; Regneron makes a variety of pharmaceuticals; and Booking Holdings owns Priceline.com, OPenTable, and other fare aggregators.